Zebrafish Genome Helps in Hunt for Treatments
“We have been waiting for this [genome] for some time,” says molecular geneticist Nicholas Katsanis. He and his team use the fish to understand the effects of mutations they ...

Genomic medicine promises to radically alter healthcare. By understanding the predictive power of patients' genomes and the products of those genomes, it should be possible to identify individuals at risk of disease and to create smarter, more effective treatments for those who are already ill.
The IGSP's research in genomic medicine is dedicated to making that happen. The strategy is to bring together programs, initiatives and experts working in various areas of medicine – from cardiovascular and infectious disease to cancer and primary care – all dedicated to translating genomic information into practical tools designed to inform clinical decision making and medical practice. It is our overarching aim to open up a pipeline of progress, allowing genomic advances to flow from discovery to translation to implementation.
As a foundational element, the IGSP has created a multi-disciplinary Clinical Genomics Studies Unit (CGSU) to design and execute genome-inspired clinical trials. We also rely on The Duke IGSP Biospecimen Repository, a standardized, regulatory compliant and privacy protected repository for fluid and tissue specimens and a newly designated Point of Care Molecular Diagnostics Development Laboratory that is a joint effort of the IGSP and the Pratt School of Engineering.
“We have been waiting for this [genome] for some time,” says molecular geneticist Nicholas Katsanis. He and his team use the fish to understand the effects of mutations they ...
“Researchers really distrust Myriad,” Cook-Deegan says. “Asking Myriad whether what you’re doing is okay would be like calling up Darth Vader to say you’re traveling near ...
An international research collaboration has found five new regions of the human genome that are linked to increased risks for developing ovarian cancer.
Two teams from Duke Medicine and its Center for Personalized Medicine have won research funding from the US Air Force Medical Support Agency for efforts to explore the use of ...
Geoff Ginsburg is a collaborator on a study introducing a new constrained model and the corresponding algorithm to identify biological signatures from high-dimensional assays like gene ...
Art Moseley and colleagues present a proof-of-concept study demonstrating the complementary nature of proteomic and genomic techniques for investigating airway (patho)physiology.
Ashley Chi and colleagues report a novel iron-responsive mechanism for the post-transcriptional regulation of ferroportin, mediated by miR-485-3p, which is induced during iron ...
Geoff Ginsburg is an author of a report aimed to engage the scientific community in providing a vision for cancer epidemiology in the 21st century.
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