Uncoupling of genomic and epigenetic signals in the maintenance and inheritance of heterochromatin domains in fission yeast.
Wheeler BS, Ruderman BT, Willard HF, Scott KC, Genetics. 2012 Feb;190(2):549-57. Abstract
IGSP Faculty
Kristin C. Scott, PhDKristin C. Scott, PhD
Assistant Research Professor, Institute for Genome Sciences & Policy
Kristin C. Scott, PhD is an Assistant Research Professor in the IGSP. She received her PhD in Biochemistry from the University of Iowa. She subsequently completed postdoctoral training at the MRC Human Genetics Unit (Edinburgh, Scotland) and at Case Western Reserve University studying centromeric heterochromatin in the fission yeast. Dr. Scott's post-doctoral training was supported by a Hitchings-Elion Fellowship from the Burroughs Wellcome Fund. Prior to joining the faculty in the Genome Biology Group in 2008, Dr. Scott was an IGSP Senior Scientist in the lab of Prof. Huntington Willard.
Research Statement
Dr. Scott's research interests involve exploring both the genetic and epigenetic basis for formation and function of centromeric heterochromatin in the fission yeast, Schizosaccaromyces pombe. Her work has defined genomic elements that serve to delineate different chromatin types in the yeast genome and provide models for understanding transitions between heterochromatin and euchromatin in complex eukaryotic genomes.
Learn more about Dr. Scott's research in GenomeLIFE
Recent Publications
The prevalence and regulation of antisense transcripts in Schizosaccharomyces pombe.
Ni T, Tu K, Wang Z, Song S, Wu H, Xie B, Scott KC, Grewal SI, Gao Y, Zhu J, PLoS One. 2010;5(12):e15271. Abstract
The impact of local genome sequence on defining heterochromatin domains.
Wheeler BS, Blau JA, Willard HF, Scott KC, PLoS Genet. 2009 Apr;5(4):e1000453. Abstract
An RNA polymerase III-dependent heterochromatin barrier at fission yeast centromere 1.
Scott KC, White CV, Willard HF, PLoS One. 2007;2(10):e1099. Abstract
A heterochromatin barrier partitions the fission yeast centromere into discrete chromatin domains.
Scott KC, Merrett SL, Willard HF, Curr Biol. 2006 Jan 24;16(2):119-29. Abstract
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